It is the first 3D computer-animated film to be rated R by the Motion Picture Association of America. The film received generally positive reviews from critics, who praised its humor and screenplay. Unbeknownst to humans, a supermarket called Shopwell’s is filled with anthropomorphic grocery items that believe that bear summer sausage human shoppers are gods who take purchased groceries to a utopia known as the “Great Beyond”.
Frank and Brenda’s packages are purchased by a female shopper. On their way out of the store, a returned jar of honey mustard tries to warn the groceries that the Great Beyond is not what it is said to be, but nobody listens except Frank. Before committing suicide by falling onto the shop floor, Honey Mustard tells Frank to seek out a bottle of liquor named Firewater. Seeking to verify Honey Mustard’s warning, Frank leads Brenda, Sammy and Lavash to the store’s liquor aisle. There, he meets Firewater and learns that Firewater and his colleagues, the Non-Perishables, created the white lie of the Great Beyond to assuage the inhabitants’ fear of being eaten.
Meanwhile, at the shopper’s house, Carl and Barry are horrified to see the shopper eat all of the foods. Carl spots a nearby open window but he is killed from being stabbed and sliced upwards by the shopper, leaving Barry to escape alone. Barry then encounters a human drug addict, who becomes able to communicate with his groceries, one of them being Gum, a Stephen Hawking-like wad of chewing gum, after injecting himself with bath salts. However, the bath salts soon wear off and the addict prepares to cook Barry.